Document Detail

Measurement of fetal surfactant production by fluorescence polarization of amniotic fluid in complicated pregnancies.
MedLine Citation:
PMID:  3119258     Owner:  NLM     Status:  MEDLINE    
The results are presented of fluorescence polarization as a method for measurement of surfactant production in 159 specimens of amniotic fluid collected from pregnant women with diabetes, hypertension, Rh immunization, premature rupture of membranes (for more than 48 h prior to delivery) and intrauterine growth retardation (IUGR). The predictability of the development of respiratory distress syndrome has been assessed by this assay. Its specificity, sensitivity and overall accuracy were similar to the lecithin/sphingomyelin (L/S) ratio. The influence of the conditions detailed on fetal lung maturation was determined, lung development being enhanced until near term by Rh immunization, rupture of membranes and hypertension with IUGR.
P Masturzo; M Salmona; G Rossi; M Luerti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinica chimica acta; international journal of clinical chemistry     Volume:  168     ISSN:  0009-8981     ISO Abbreviation:  Clin. Chim. Acta     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1988-01-14     Completed Date:  1988-01-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1302422     Medline TA:  Clin Chim Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  137-42     Citation Subset:  IM    
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
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MeSH Terms
Amniotic Fluid / analysis*
Fetal Growth Retardation / metabolism
Fetal Membranes, Premature Rupture / metabolism
Fetus / metabolism*
Fluorescence Polarization
Hypertension / complications,  metabolism
Pregnancy Complications*
Pregnancy in Diabetics / metabolism
Pulmonary Surfactants / biosynthesis*
Rh Isoimmunization / metabolism
Reg. No./Substance:
0/Pulmonary Surfactants

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