Document Detail


Measurement of diffusion of uncharged molecules in articular cartilage.
MedLine Citation:
PMID:  6205821     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The diffusion of glucose (180 M.W.), inulin (5,000 M.W.) and dextran (20,000 M.W.) into mature bovine and equine articular cartilage was studied. Concentration profiles were determined using a one-dimensional experimental configuration and the diffusion coefficient and partition coefficient calculated from a theoretical model. Glucose was found to diffuse the fastest, followed by inulin and dextran. The partition coefficient was similarly ordered. The rate of diffusion was found to decrease with increasing diffusion time, indicating a dependence on solute concentration. No time variation was evident in the partition coefficient. In addition, no difference was found between species or between the location sites within the animal joint.
Authors:
R V Allhands; P A Torzilli; F A Kallfelz
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Cornell veterinarian     Volume:  74     ISSN:  0010-8901     ISO Abbreviation:  Cornell Vet     Publication Date:  1984 Apr 
Date Detail:
Created Date:  1984-09-24     Completed Date:  1984-09-24     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0074245     Medline TA:  Cornell Vet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  111-23     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cartilage, Articular / metabolism*
Cattle
Dextrans / metabolism*
Diffusion
Glucose / metabolism*
Horses
Inulin / metabolism*
Molecular Weight
Time Factors
Grant Support
ID/Acronym/Agency:
AM05778/AM/NIADDK NIH HHS; AM19849/AM/NIADDK NIH HHS
Chemical
Reg. No./Substance:
50-99-7/Glucose; 9004-54-0/Dextrans; 9005-80-5/Inulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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