Document Detail

Measurement of cerebral blood flow (CBF) with the Kety and Schmidt technique during craniotomy.
MedLine Citation:
PMID:  1843839     Owner:  NLM     Status:  MEDLINE    
In this study cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2) were measured twice during craniotomy for supratentorial cerebral tumors by the Kety and Schmidt technique. The anaesthetic procedures included halothane, enflurane isoflurane and continuous infusion with midazolam, etomidate, althesin and neurolept anaesthesia (dehydrobenzpyridol). Moderate hypocapnia was used and the anaesthesia was supplemented with nitrous oxide and fentanyl. In general, both CBF and CMRO2 were decreased. However, with inhalation anaesthetics an increase in concentration resulted in an increase in CBF (halothane) or unchanged CBF (isoflurane and enflurane) and a decrease in CMRO2. With the hypnotic agents a dose related decrease in CMRO2 was observed, while CBF either was unchanged (midazolam) or decreased (Althesin and etomidate).
G E Cold; J B Madsen; L Knudsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Agressologie: revue internationale de physio-biologie et de pharmacologie appliquées aux effets de l'agression     Volume:  32     ISSN:  0002-1148     ISO Abbreviation:  Agressologie     Publication Date:  1991  
Date Detail:
Created Date:  1993-03-23     Completed Date:  1993-03-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0121575     Medline TA:  Agressologie     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  345-51     Citation Subset:  IM    
Department of Neuroanaesthesia, Arhus Kommunehospital, Copenhagen, Denmark.
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MeSH Terms
Anesthesia, General / methods
Anesthetics / pharmacology*
Blood Flow Velocity
Brain / metabolism
Cerebrovascular Circulation / drug effects*
Middle Aged
Oxygen Consumption / drug effects
Reg. No./Substance:

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