Document Detail

Measurement of cardiac output by real-time 3D echocardiography in patients undergoing assessment for cardiac transplantation.
MedLine Citation:
PMID:  17618836     Owner:  NLM     Status:  MEDLINE    
AIMS: Heart transplant assessment includes cardiac output calculation by right heart catheterisation. Real-time 3D echocardiography (RT-3DE), unlike 2D echocardiography, can measure stroke volume without inaccurate geometrical assumptions. The purpose of this study was to assess the feasibility and accuracy of non-invasive RT-3DE cardiac output calculation. METHODS AND RESULTS: Forty consecutive patients referred for transplant assessment underwent transthoracic RT-3DE. Full volume 3DE data sets were acquired from apical views with the iE33 ultrasound system (Philips Ultrasound, Bothell, USA). Four patients were excluded due to poor image quality. The remaining 36 patients had end-diastolic (LVEDV) and end-systolic (LVESV) left ventricular volumes manually traced, using endocardial detection software. Cardiac output was subsequently calculated: [(LVEDV - LVESV) x heart rate]. Thermodilution derived cardiac outputs, under the same haemodynamic conditions, were used as reference for comparison. There was close correlation between RT-3DE and catheter derived cardiac outputs (r = 0.91, y = 0.86x + 0.45, SEE 0.39 L/min, mean difference from reference -0.06 L/min, SD 0.40 L/min). RT-3DE data analysis took 3 min per case. CONCLUSION: This study shows RT-3DE is an accurate method for calculating cardiac output. In patients requiring serial evaluation of cardiac function, this non-invasive test may be preferable to invasive right heart catheterisation.
Stephen P Hoole; James Boyd; Vlasis Ninios; Jayan Parameshwar; Rosemary A Rusk
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Publication Detail:
Type:  Journal Article     Date:  2007-07-09
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  9     ISSN:  1532-2114     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-20     Completed Date:  2008-08-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  334-7     Citation Subset:  IM    
Department of Echocardiography, Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridgeshire CB23 8RE, UK.
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MeSH Terms
Cardiac Output
Cardiomyopathies / surgery,  ultrasonography*
Echocardiography, Three-Dimensional*
Feasibility Studies
Heart Transplantation*
Middle Aged

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