| Measurement of body composition in cats using computed tomography and dual energy x-ray absorptiometry. | |
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MedLine Citation:
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PMID: 21388470 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Dual energy X-ray absorptiometry (DEXA) is a reference method for assessing body composition but is seldom `accessible in veterinary settings. Computed tomography (CT) can provide similar body composition estimates and we propose that it can be used in body composition studies in animals. We compared CT and DEXA data from 73 healthy adult neutered domestic cats. Three approaches for measuring adipose tissue percentage from full-body CT scans were explored. By examining the frequency distribution of voxels by Hounsfield unit (HU) value, it is possible to calculate a fat index (Fat%) that is in close agreement with the fat percentages obtained from DEXA scans. Fat% values obtained by the best of the methods had a mean difference of 0.96% (95% confidence interval 0.33-1.59%) from the DEXA results. Fat% obtained by the other two methods were characterized by good correlation but poor agreement and in one of the methods, the difference between the values from the two modalities was proportional to their mean. By using CT, it is possible to obtain body composition estimates that are in close agreement with those available using DEXA. While the significance of individual Fat% measurements obtained from CT can be difficult to interpret and to compare between centers, CT can contribute to research studies concerned either with nutrition or with obesity-related disorders. |
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Authors:
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Lene E Buelund; Dorte H Nielsen; Fintan J McEvoy; Eiliv L Svalastoga; Charlotte R Bjornvad |
Publication Detail:
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Type: Journal Article Date: 2010-11-11 |
Journal Detail:
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Title: Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association Volume: 52 ISSN: 1058-8183 ISO Abbreviation: Vet Radiol Ultrasound Publication Date: 2011 Mar-Apr |
Date Detail:
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Created Date: 2011-03-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9209635 Medline TA: Vet Radiol Ultrasound Country: United States |
Other Details:
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Languages: eng Pagination: 179-84 Citation Subset: IM |
Copyright Information:
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© 2010 Veterinary Radiology & Ultrasound. |
Affiliation:
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Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Dyrlaegevej 16, 1870 Frederiksberg C, Denmark. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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