| Measurement of pulmonary circulation parameters using time-resolved MR angiography in patients after Ross procedure. | |
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MedLine Citation:
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PMID: 20308491 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purposes of our study were to retrospectively evaluate the pulmonary circulation parameters of pulmonary transit time and pulmonary blood volume in patients after Ross procedures using time-resolved MR angiography and to investigate associations with right ventricular dysfunction in the same group of patients. MATERIALS AND METHODS: Sixteen patients who had undergone a Ross procedure (12 men, four women; mean age, 42.13 +/- 14.24 years; age range, 21-68 years) and 16 age- and sex-matched control patients (12 men, 4 women; mean age, 42.25 +/- 14.62 years; age range, 21-68 years) were evaluated using cardiac MRI and Argus postprocessing software. Right and left ventricular volumetric parameters, including ejection fraction, end-systolic volume, and end-diastolic volume, were measured from cine true fast imaging with steady-state precession images. Pulmonary circulation parameters, including pulmonary transit time, were measured using dynamic time-resolved MR angiography and pulmonary blood volume was calculated. Pulmonary circulation parameters were correlated with volumetric parameters. The results were statistically analyzed using the Mann-Whitney U test, paired-samples Student's t test, Pearson's correlation, and linear regression. RESULTS: Pulmonary circulation parameters were significantly prolonged in patients after the Ross procedure compared with control patients (p < 0.01). Strong correlations exist between pulmonary circulation parameters and right ventricular function, especially pulmonary transit time and right ventricular ejection fraction (R > 0.60, p < 0.001). CONCLUSION: Patients after undergoing the Ross procedure had prolonged pulmonary transit times compared with normal control patients; this and other pulmonary circulation parameters best correlate with worsened right ventricular ejection fraction and may be predictors of right ventricular dysfunction in this group of patients. |
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Authors:
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Anna Lakoma; David Tuite; John Sheehan; Peter Weale; James C Carr |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 194 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-23 Completed Date: 2010-05-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 912-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Northwestern University, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aortic Valve Insufficiency / surgery* Blood Flow Velocity Blood Volume Cardiac Surgical Procedures* Case-Control Studies Contrast Media Diastole Female Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Linear Models Magnetic Resonance Angiography / methods* Male Middle Aged Postoperative Complications / diagnosis Pulmonary Circulation* Retrospective Studies Statistics, Nonparametric Stroke Volume Systole Ventricular Dysfunction, Left / surgery* Ventricular Dysfunction, Right / diagnosis* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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