| The measurement of hemodialysis access blood flow by a conductivity step method. | |
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MedLine Citation:
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PMID: 20616158 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVES: Measurement of blood flow rate (Qa) is used to monitor dialysis access, AV fistulas, and grafts. Indicator dilution measurements of the recirculation (R) induced by reversal of hemodialysis blood lines are commonly used. This plus the dialysis circuit flow (Qb) allows calculation of Qa. R also changes the conductivity, which can be measured by a conductivity cell in the spent dialysate. The change in conductivity caused by line reversal should vary with Qa. A methodology for Qa measurement utilizing this conductivity step is proposed. This study compares conductivity step methodology against the reference method of ultrasound dilution (Qa-Trans). DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This was an open diagnostic test study in a single academic hospital setting involving 15 hemodialysis-dependent patients. Each was studied over four hemodialysis treatments. During each treatment, two pairs of Qa measurements (conductivity step and Trans) were made. Pre- and postdialysis sodium levels were also measured. RESULTS: Average Qa-conductivity step was 1040 ml/min. Average Qa-Trans was 1030 ml/min. The difference was NS. The data pairs showed mean difference of 1.3 +/- 17% (SD). The SD indicates a relatively large variation between data pairs. There was significant linear correlation between the Qa-conductivity step and Qa-Trans results (r = 0.91, P < 0.001). Serum sodium rose slightly but significantly over dialysis (P < 0.001). CONCLUSIONS: Qa measurement by conductivity step may be an acceptable alternative to ultrasound dilution methodology. Care must be taken to prevent salt loading when the conductivity step is used. |
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Authors:
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Robert M Lindsay; Shih-Han S Huang; Jan Sternby; Thomas Hertz |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-07-08 |
Journal Detail:
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Title: Clinical journal of the American Society of Nephrology : CJASN Volume: 5 ISSN: 1555-905X ISO Abbreviation: Clin J Am Soc Nephrol Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-08 Completed Date: 2011-01-11 Revised Date: 2011-09-13 |
Medline Journal Info:
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Nlm Unique ID: 101271570 Medline TA: Clin J Am Soc Nephrol Country: United States |
Other Details:
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Languages: eng Pagination: 1602-6 Citation Subset: IM |
Affiliation:
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London Health Sciences Centre and the University of Western Ontario, London, Ontario, Canada. robert.lindsay@lhsc.on.ca |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Arteriovenous Shunt, Surgical* Biological Markers / blood Blood Flow Velocity Blood Vessel Prosthesis Implantation* Dialysis Solutions / chemistry* Electric Conductivity* Female Hospitals, University Humans Indicator Dilution Techniques* Male Ontario Predictive Value of Tests Regional Blood Flow Renal Dialysis* Sodium / blood Ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Dialysis Solutions; 7440-23-5/Sodium |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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