Document Detail


Measurement of Focal Ground-glass Opacity Diameters on CT Images Interobserver Agreement in Regard to Identifying Increases in the Size of Ground-Glass Opacities.
MedLine Citation:
PMID:  22222027     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To evaluate interobserver agreement in regard to measurements of focal ground-glass opacities (GGO) diameters on computed tomography (CT) images to identify increases in the size of GGOs. MATERIALS AND METHODS: Approval by the institutional review board and informed consent by the patients were obtained. Ten GGOs (mean size, 10.4 mm; range, 6.5-15 mm), one each in 10 patients (mean age, 65.9 years; range, 58-78 years), were used to make the diameter measurements. Eleven radiologists independently measured the diameters of the GGOs on a total of 40 thin-section CT images (the first [n = 10], the second [n = 10], and the third [n = 10] follow-up CT examinations and remeasurement of the first [n = 10] follow-up CT examinations) without comparing time-lapse CT images. Interobserver agreement was assessed by means of Bland-Altman plots. RESULTS: The smallest range of the 95% limits of interobserver agreement between the members of the 55 pairs of the 11 radiologists in regard to maximal diameter was -1.14 to 1.72 mm, and the largest range was -7.7 to 1.7 mm. The mean value of the lower limit of the 95% limits of agreement was -3.1 ± 1.4 mm, and the mean value of their upper limit was 2.5 ± 1.1 mm. CONCLUSION: When measurements are made by any two radiologists, an increase in the length of the maximal diameter of more than 1.72 mm would be necessary in order to be able to state that the maximal diameter of a particular GGO had actually increased.
Authors:
Ryutaro Kakinuma; Kazuto Ashizawa; Keiko Kuriyama; Aya Fukushima; Hiroyuki Ishikawa; Hisashi Kamiya; Naoya Koizumi; Yuichiro Maruyama; Kazunori Minami; Norihisa Nitta; Seitaro Oda; Yasuji Oshiro; Masahiko Kusumoto; Sadayuki Murayama; Kiyoshi Murata; Yukio Muramatsu; Noriyuki Moriyama
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-3
Journal Detail:
Title:  Academic radiology     Volume:  -     ISSN:  1878-4046     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440159     Medline TA:  Acad Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 AUR. Published by Elsevier Inc. All rights reserved.
Affiliation:
National Cancer Center, Research Center for Cancer Prevention and Screening, 5-1-1 Tsukiji Chuo-ku, Tokyo, Japan.
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