Document Detail

Measured versus modeled dietary arsenic and relation to urinary arsenic excretion and total exposure.
MedLine Citation:
PMID:  23321855     Owner:  NLM     Status:  MEDLINE    
Chronic exposure to arsenic (As) in food and water is a significant public health problem. Person-specific aggregate exposure is difficult to collect and modeling based on limited food As residue databases is of uncertain reliability. Two cross-sectional population exposure studies, the National Human Exposure Assessment Survey-Arizona and Arizona Border Survey, had a combined total of 252 subjects with diet, water, and urinary As data. Total As was measured in 24-h duplicate diet samples and modeled using 24-h diet diaries in conjunction with several published food surveys of As. Two-stage regression was used to assess the effects of dietary As on urinary total As (uAs): (1) generalized linear mixed models of uAs above versus below the limit of detection (LOD); and (2) restricted models limited to those subjects with uAs>LOD, using bootstrap sampling and mixed models adjusted for age, sex, body mass index, ethnicity, current smoking, and As intake from drinking and cooking water. In restricted models, measured and modeled estimates were significant predictors of uAs. Modeled dietary As based on Total Diet Study mean residues greatly underestimated the dietary intake. In households with tap water As ≤10 p.p.b., over 93% of total arsenic exposure was attributable to diet.
Margaret Kurzius-Spencer; Mary K O'Rourke; Chiu-Hsieh Hsu; Vern Hartz; Robin B Harris; Jefferey L Burgess
Related Documents :
23713535 - Assessment of energy expenditure in elite jockeys during simulated race riding and a wo...
23487755 - Ready-to-use food-allocation policy to reduce the effects of childhood undernutrition i...
24674635 - Objective and self-reported factors associated with food-environment perceptions and fr...
12297375 - Advancing monosaccharides as biomarkers: part ii. effects of starvation and cadmium in ...
14341595 - Sequential primary and secondary shunt metabolism in penicillium chrysogenum.
8107455 - Can nutrition information increase sales of healthful vended snacks?
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2013-01-16
Journal Detail:
Title:  Journal of exposure science & environmental epidemiology     Volume:  23     ISSN:  1559-064X     ISO Abbreviation:  J Expo Sci Environ Epidemiol     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-19     Completed Date:  2013-12-09     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  101262796     Medline TA:  J Expo Sci Environ Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  442-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Arizona / epidemiology
Arsenic / urine*
Cross-Sectional Studies
Diet / adverse effects,  statistics & numerical data*
Diet Surveys
Drinking Water / analysis
Environmental Exposure / analysis*
European Continental Ancestry Group / statistics & numerical data
Hispanic Americans / statistics & numerical data
Limit of Detection
Linear Models
Middle Aged
Models, Biological
Young Adult
Grant Support
Reg. No./Substance:
0/Drinking Water; N712M78A8G/Arsenic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Photoassisted defluorination of fluorinated substrates and pharmaceuticals by a wide bandgap metal o...
Next Document:  Influence of human activity patterns, particle composition, and residential air exchange rates on mo...