Document Detail


Measles outbreaks affecting children in Jewish ultra-orthodox communities in Jerusalem.
MedLine Citation:
PMID:  17433131     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 2003 and 2004 two measles outbreaks occurred in Jewish ultra-orthodox communities in Jerusalem. The index case of the first outbreak (March 2003) was a 2-year-old unvaccinated child from Switzerland. Within 5 months, 107 cases (mean age 8.3+/-7.5 years) emerged in three crowded neighbourhoods. The first cases of the second outbreak (June 2004) were in three girls aged 4-5 years in one kindergarten in another community. By November 2004, 117 cases (mean age 7.3+/-6.5 years) occurred. The virus genotypes were D8 and D4 respectively. Altogether, 96 households accounted for the two outbreaks, with two or more patients per family in 79% of cases. Most cases (91.5%) were unvaccinated. Immunization coverage was lower in outbreak than in non-outbreak neighbourhoods (88.3% vs. 90.3%, P=0.001). Controlling the outbreaks necessitated a culture-sensitive approach, and targeted efforts increased MMR vaccine coverage (first dose) to 95.2%. Despite high national immunization coverage (94-95%), special attention to specific sub-populations is essential.
Authors:
C Stein-Zamir; G Zentner; N Abramson; H Shoob; Y Aboudy; L Shulman; E Mendelson
Publication Detail:
Type:  Journal Article     Date:  2007-04-16
Journal Detail:
Title:  Epidemiology and infection     Volume:  136     ISSN:  0950-2688     ISO Abbreviation:  Epidemiol. Infect.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-09     Completed Date:  2008-03-13     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  8703737     Medline TA:  Epidemiol Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  207-14     Citation Subset:  IM    
Affiliation:
Jerusalem District Health Office, Ministry of Health, Jerusalem, Israel. chen@lbjer.health.gov.il
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Child, Preschool
Disease Outbreaks*
Female
Genotype
Humans
Infant
Infant, Newborn
Infection Control / methods
Israel / epidemiology
Male
Measles / epidemiology*,  immunology
Measles-Mumps-Rubella Vaccine / administration & dosage,  immunology
Morbillivirus / classification*,  genetics,  isolation & purification*
Chemical
Reg. No./Substance:
0/Measles-Mumps-Rubella Vaccine
Comments/Corrections

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