Document Detail


McKittrick-Wheelock Syndrome: A Rare Cause of Life-threatening Electrolyte Disturbances and Volume Depletion.
MedLine Citation:
PMID:  20097031     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: It is uncommon for emergency physicians to discover a patient with circulatory failure resulting from chronic diarrhea. Objectives: We describe McKittrick-Wheelock syndrome, a rare disorder characterized by volume and electrolyte depletion and caused by colonic neoplasm. Case Report: The case of a 30-year-old woman who came to the Emergency Department with hypovolemic shock, hyponatremia, and hypokalemia with a background of chronic diarrhea is reported. The hypokalemia and dehydration were refractory to aggressive replacement therapy. Her condition was the result of fluid and electrolyte hypersecretion caused by a colonic adenocarcinoma and colonic polyposis. Surgical removal of the colon and subsequent volume and electrolyte replacement therapy resulted in complete recovery. Conclusion: This case is presented to increase awareness among emergency physicians of the rare disorder of McKittrick-Wheelock syndrome.
Authors:
Yu-Sung Lee; Hung-Jung Lin; Kuo-Tai Chen
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-1-21
Journal Detail:
Title:  The Journal of emergency medicine     Volume:  -     ISSN:  0736-4679     ISO Abbreviation:  -     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-1-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8412174     Medline TA:  J Emerg Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2009 Elsevier Inc. All rights reserved.
Affiliation:
Department of Emergency Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
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