| McClintock's challenge in the 21st century. | |
| | |
MedLine Citation:
|
PMID: 23150590 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In 1950, Barbara McClintock published a Classic PNAS article, "The origin and behavior of mutable loci in maize," which summarized the evidence leading to her discovery of transposition. The article described a number of genome alterations revealed through her studies of the Dissociation locus, the first mobile genetic element she identified. McClintock described the suite of nuclear events, including transposon activation and various chromosome aberrations and rearrangements, that unfolded in the wake of genetic crosses that brought together two broken chromosomes 9. McClintock left future generations with the challenge of understanding how genomes respond to genetic and environmental stresses by mounting adaptive responses that frequently include genome restructuring. |
| | |
Authors:
|
Nina V Fedoroff |
Publication Detail:
|
Type: Biography; Historical Article; Journal Article Date: 2012-11-13 |
Journal Detail:
|
Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 109 ISSN: 1091-6490 ISO Abbreviation: Proc. Natl. Acad. Sci. U.S.A. Publication Date: 2012 Dec |
Date Detail:
|
Created Date: 2012-12-13 Completed Date: 2013-02-28 Revised Date: 2013-06-12 |
Medline Journal Info:
|
Nlm Unique ID: 7505876 Medline TA: Proc Natl Acad Sci U S A Country: United States |
Other Details:
|
Languages: eng Pagination: 20200-3 Citation Subset: IM |
Affiliation:
|
Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal 23955-6900, Saudi Arabia. nvf1@psu.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Chromosome Breakage Chromosomes, Plant / genetics DNA Transposable Elements / genetics Epigenesis, Genetic Genome, Plant History, 20th Century History, 21st Century Molecular Biology / history*, trends Phenotype Zea mays / genetics |
| Chemical | |
Reg. No./Substance:
|
0/DNA Transposable Elements |
| Personal Name Subject | |
Personal Name Subject:
|
Barbara McClintock |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hydroperiod regime controls the organization of plant species in wetlands.
Next Document: Carbon and other light element contents in the Earth's core based on first-principles molecular dyna...