Document Detail


May-Thurner syndrome will be completed?
MedLine Citation:
PMID:  18479739     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The May-Thurner syndrome is a deep venous thrombosis of the left iliofemoral vein due to a compression by the right primitive iliac artery. Some authors suggested that this syndrome could be associated with genetics factors predisposing to thrombophilia. OBJECTIVES: The aim of this article is to assess if the May-Thurner syndrome could be associated with inherited thombophilia particularly the factor V mutation. PATIENTS/METHODS: We exposed three cases of May-Thurner syndrome, all were positive for the presence of factor V Leiden. CONCLUSION: Some olds syndromes can be revisited and explained by molecular research. In this case, the May-Thurner syndrome could be associated with inherited thrombophilia. This finding could explain the pathology but also open new treatments or guidelines for the management this kind of pathology.
Authors:
Yann De Bast; Laurent Dahin
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-05-13
Journal Detail:
Title:  Thrombosis research     Volume:  123     ISSN:  0049-3848     ISO Abbreviation:  Thromb. Res.     Publication Date:  2009  
Date Detail:
Created Date:  2008-12-29     Completed Date:  2009-04-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326377     Medline TA:  Thromb Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  498-502     Citation Subset:  IM    
Affiliation:
Vascular Surgery department, Saint Anne Saint Remi Clinic, Brussels, Belgium. ydebast@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Factor V / genetics*
Female
Femoral Vein
Humans
Iliac Artery
Ilium
Lumbosacral Region
Point Mutation*
Prothrombin / genetics*
Syndrome
Thrombophilia / blood,  complications,  genetics
Tomography, X-Ray Computed
Venous Thrombosis / blood,  etiology*,  genetics*,  radiography
Young Adult
Chemical
Reg. No./Substance:
0/factor V Leiden; 9001-24-5/Factor V; 9001-26-7/Prothrombin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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