Document Detail

May-Thurner syndrome will be completed?
MedLine Citation:
PMID:  18479739     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The May-Thurner syndrome is a deep venous thrombosis of the left iliofemoral vein due to a compression by the right primitive iliac artery. Some authors suggested that this syndrome could be associated with genetics factors predisposing to thrombophilia. OBJECTIVES: The aim of this article is to assess if the May-Thurner syndrome could be associated with inherited thombophilia particularly the factor V mutation. PATIENTS/METHODS: We exposed three cases of May-Thurner syndrome, all were positive for the presence of factor V Leiden. CONCLUSION: Some olds syndromes can be revisited and explained by molecular research. In this case, the May-Thurner syndrome could be associated with inherited thrombophilia. This finding could explain the pathology but also open new treatments or guidelines for the management this kind of pathology.
Yann De Bast; Laurent Dahin
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-05-13
Journal Detail:
Title:  Thrombosis research     Volume:  123     ISSN:  0049-3848     ISO Abbreviation:  Thromb. Res.     Publication Date:  2009  
Date Detail:
Created Date:  2008-12-29     Completed Date:  2009-04-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326377     Medline TA:  Thromb Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  498-502     Citation Subset:  IM    
Vascular Surgery department, Saint Anne Saint Remi Clinic, Brussels, Belgium.
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MeSH Terms
Factor V / genetics*
Femoral Vein
Iliac Artery
Lumbosacral Region
Point Mutation*
Prothrombin / genetics*
Thrombophilia / blood,  complications,  genetics
Tomography, X-Ray Computed
Venous Thrombosis / blood,  etiology*,  genetics*,  radiography
Young Adult
Reg. No./Substance:
0/factor V Leiden; 9001-24-5/Factor V; 9001-26-7/Prothrombin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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