| Maximum variance of late component event related potentials (190-240 ms) in unmedicated schizophrenic patients. | |
| | |
MedLine Citation:
|
PMID: 7568545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The averaging of individual late component event related potential (ERP) responses, particularly P300, has revealed significant differences between schizophrenic patients and normal subjects. However, the averaging process removes the variability of the individual epochs that constitute that average. The response-variance-curve (RVC) method quantifies the variability of the individual epochs and allows examinations of windows of maximum variance. In this study, we examine the complementary nature of the RVC method to the traditional averaging approach. The averaged N200 and P300 ERP components differed significantly between the schizophrenic and normal groups, but not between the unmedicated and medicated schizophrenic patients. The RVC measure, on the other hand, revealed systematic differences in variability, maximal between 190 and 240 ms, between the unmedicated and medicated schizophrenic patients. The RVC measure therefore provides a focused time frame in which to examine dysfunctions in information processing and macroscopic scale changes in brain function due to medication. |
| | |
Authors:
|
J Anderson; E Gordon; R J Barry; C Rennie; P J Beumont; R Meares |
Related Documents
:
|
15764435 - Reading about over-the-counter medications. 7979145 - Specialist training and certification process for anaesthesiologist in japan. 9793835 - Dr. john frederick may and the identification of john wilkes booth's body. 11503655 - Physical qualification of drivers; medical examination; certificate. federal motor carr... 16529625 - Discontinuation of anticonvulsant medication after epilepsy surgery in children. 15544295 - The surgical illustrator: a web enabled computer program for documenting clinical and p... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Psychiatry research Volume: 56 ISSN: 0165-1781 ISO Abbreviation: Psychiatry Res Publication Date: 1995 Apr |
Date Detail:
|
Created Date: 1995-11-21 Completed Date: 1995-11-21 Revised Date: 2008-04-17 |
Medline Journal Info:
|
Nlm Unique ID: 7911385 Medline TA: Psychiatry Res Country: IRELAND |
Other Details:
|
Languages: eng Pagination: 229-36 Citation Subset: IM |
Affiliation:
|
Department of Psychiatry, University of Sydney, Westmead Hospital, NSW, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acoustic Stimulation Adult Analysis of Variance Evoked Potentials, Auditory / physiology* Humans Psychiatric Status Rating Scales Schizophrenia / physiopathology* Schizophrenic Psychology Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of light therapy on salivary melatonin in seasonal affective disorder.
Next Document: Event related response variability in schizophrenia: effect of intratrial target subsets.