Document Detail

Maximum linear-phase spectral-spatial radiofrequency pulses for fat-suppressed proton resonance frequency-shift MR Thermometry.
MedLine Citation:
PMID:  19780177     Owner:  NLM     Status:  MEDLINE    
Conventional spectral-spatial pulses used for water-selective excitation in proton resonance frequency-shift MR thermometry require increased sequence length compared to shorter wideband pulses. This is because spectral-spatial pulses are longer than wideband pulses, and the echo time period starts midway through them. Therefore, for a fixed echo time, one must increase sequence length to accommodate conventional spectral-spatial pulses in proton resonance frequency-shift thermometry. We introduce improved water-selective spectral-spatial pulses for which the echo time period starts near the beginning of excitation. Instead of requiring increased sequence length, these pulses extend into the long echo time periods common to PRF sequences. The new pulses therefore alleviate the traditional tradeoff between sequence length and fat suppression. We experimentally demonstrate an 11% improvement in frame rate in a proton resonance frequency imaging sequence compared to conventional spectral-spatial excitation. We also introduce a novel spectral-spatial pulse design technique that is a hybrid of previous model- and filter-based techniques and that inherits advantages from both. We experimentally validate the pulses' performance in suppressing lipid signal and in reducing sequence length compared to conventional spectral-spatial pulses.
William A Grissom; Adam B Kerr; Andrew B Holbrook; John M Pauly; Kim Butts-Pauly
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  62     ISSN:  1522-2594     ISO Abbreviation:  Magn Reson Med     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-03     Completed Date:  2010-01-13     Revised Date:  2014-09-13    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1242-50     Citation Subset:  IM    
Copyright Information:
(c) 2009 Wiley-Liss, Inc.
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MeSH Terms
Adipose Tissue / anatomy & histology*,  physiology*
Body Temperature / physiology*
Image Interpretation, Computer-Assisted / methods*
Magnetic Resonance Imaging / instrumentation,  methods*
Magnetic Resonance Spectroscopy / instrumentation,  methods*
Phantoms, Imaging
Reproducibility of Results
Sensitivity and Specificity
Thermography / methods*
Grant Support
P01 CA067165/CA/NCI NIH HHS; P01 CA067165/CA/NCI NIH HHS; P01 CA067165-11/CA/NCI NIH HHS; R01 CA111981/CA/NCI NIH HHS; R01 CA111981/CA/NCI NIH HHS; R01 CA111981-05/CA/NCI NIH HHS; R01 CA121163/CA/NCI NIH HHS; R01 CA121163/CA/NCI NIH HHS; R01 CA121163-04/CA/NCI NIH HHS; U41 RR019703/RR/NCRR NIH HHS; U41 RR019703/RR/NCRR NIH HHS; U41 RR019703-02/RR/NCRR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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