| Maximizing the hemodynamic benefit of enhanced external counterpulsation. | |
| | |
MedLine Citation:
|
PMID: 9755381 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Enhanced external counterpulsation (EECP) has been demonstrated to be an effective treatment for angina and exertional ischemia in patients with coronary disease. HYPOTHESIS: It is hypothesized that the ability of EECP to enhance the recruitment or development of coronary collaterals in coronary artery disease may be determined by the relative magnitude of diastolic augmentation (DA) and systolic unloading (SU). This study examines the relation between the proposed EECP effectiveness ratio (DA/SU), as assessed by finger plethysmography, and changes in descending aortic flow as assessed by Doppler echocardiography in 15 patients during EECP. METHODS: Varying external cuff pressures (0-275 mmHg) were used to generate a range of DA/SU ratios. The effect on aortic antegrade systolic and retrograde diastolic flow was assessed by Doppler echocardiography to determine whether there was an optimal EECP effectiveness ratio that maximizes the hemodynamic effects of EECP. With increasing DA/SU there was an initial positive linear increase in both systolic and diastolic flow volume. Systolic flow maximized at an effectiveness ratio of 1.5 and diastolic flow at a ratio of 2.0 RESULT: Therefore, effectiveness ratios (DA/SU) in the range of 1.5-2.0 are optimal for maximizing the hemodynamic effects of EECP. |
| | |
Authors:
|
K Suresh; S Simandl; W E Lawson; J C Hui; O Lillis; L Burger; T Guo; P F Cohn |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Clinical cardiology Volume: 21 ISSN: 0160-9289 ISO Abbreviation: Clin Cardiol Publication Date: 1998 Sep |
Date Detail:
|
Created Date: 1998-11-25 Completed Date: 1998-11-25 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7903272 Medline TA: Clin Cardiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 649-53 Citation Subset: IM |
Affiliation:
|
Division of Cardiology, SUNY, Health Sciences Center, Stony Brook 11794, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Angina Pectoris / physiopathology*, therapy* Cardiac Output Counterpulsation / methods* Echocardiography, Doppler, Pulsed Female Hemodynamics* Humans Male Middle Aged Myocardial Ischemia / physiopathology*, therapy* Plethysmography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A comparative study of eccentric and concentric coronary stenosis vasomotion in patients with Prinzm...
Next Document: Serum amyloid type A may be a predictor of restenosis.