| Maximising recruitment and retention of general practices in clinical trials: a case study. | |
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MedLine Citation:
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PMID: 19000399 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: There is limited evidence regarding the factors that facilitate recruitment and retention of general practices in clinical trials. It is therefore pertinent to consider the factors that facilitate research in primary care. AIM: To formulate hypotheses about effective ways of recruiting and retaining practices to clinical trials, based on a case study. DESIGN OF STUDY: Case study of practice recruitment and retention to a trial of delivering antenatal sickle cell and thalassaemia screening. SETTING: Two UK primary care trusts with 123 practices, with a high incidence of sickle cell and thalassaemia, and high levels of social deprivation. METHOD: Practices were invited to take part in the trial using a research information sheet for practices. Invitations were sent to all practice managers, GPs, practice nurses, and nurse practitioners. Expenses of approximately pound 3000 per practice were available. Practices and the research team signed research activity agreements, detailing a payment schedule based on deliverables. Semi-structured interviews were completed with 20 GPs who participated in the trial. Outcome measures were the number of practices recruited to, and completing, the trial. RESULTS: Four practices did not agree to randomisation and were excluded. Of 119 eligible practices, 29 expressed an interest in participation. Two practices withdrew from the trial and 27 participated (two hosted pilot studies and 25 completed the trial), giving a retention rate of 93% (27/29). The 27 participating practices did not differ from non-participating practices in list size, number of GPs, social deprivation, or minority ethnic group composition of the practice population. CONCLUSION: Three factors appeared important in recruiting practices: research topic, invitation method, and interest in research. Three factors appeared important in retaining practices: good communication, easy data-collection methods, and payment upon meeting pre-agreed targets. The effectiveness of these factors at facilitating recruitment and retention requires assessment in experimental studies. |
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Authors:
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Elizabeth Dormandy; Fred Kavalier; Jane Logan; Hilary Harris; Nola Ishmael; Theresa M Marteau; |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The British journal of general practice : the journal of the Royal College of General Practitioners Volume: 58 ISSN: 1478-5242 ISO Abbreviation: Br J Gen Pract Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-12 Completed Date: 2008-12-22 Revised Date: 2010-11-04 |
Medline Journal Info:
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Nlm Unique ID: 9005323 Medline TA: Br J Gen Pract Country: England |
Other Details:
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Languages: eng Pagination: 759-66, i-ii Citation Subset: IM |
Affiliation:
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Department of Clinical Genetics, King's College London, London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Sickle Cell
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prevention & control Attitude of Health Personnel* Family Practice / economics, organization & administration* Female Humans Interdisciplinary Communication Pregnancy Pregnancy Complications, Hematologic / prevention & control Randomized Controlled Trials as Topic* Socioeconomic Factors Thalassemia / prevention & control |
| Grant Support | |
ID/Acronym/Agency:
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03/02/03//Department of Health; HTA_275//Department of Health |
| Investigator | |
Investigator/Affiliation:
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A E Ades / ; Elizabeth N Anionwu / ; Karl Atkin / ; Katrina Brown / ; Stirling Bryan / ; Mike Calnan / ; Verna Davis / ; Moira Dick / ; Martin Gulliford / ; Tracey Johnston / ; Patricia Jones / ; Jon Karnon / ; Erin P Reid / ; Tracy Roberts / ; Barbara Wild / |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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