| Maximal oxygen uptake and erythropoietic responses after training at moderate altitude. | |
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MedLine Citation:
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PMID: 1874246 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Six well-trained male cross-county skiers trained for 7 days at 2700 m above sea level, their accommodation being at 1695 m. Blood samples for haemoglobin concentration [Hb], erythropoietin concentration [EPO] and reticulocyte count were collected before, during and after altitude exposure. Packed cell volume (PCV), red blood cell count (RBC), transferrin-iron saturation, mean red cell volume (MCV), mean corpuscular haemoglobin concentration (MCHC), maximal oxygen uptake, maximal achieved ventilation and heart rate were determined pre- and postaltitude exposure. The [EPO] increased significantly from pre-altitude (mean 36 mU.ml-1, SD 5) to maximal altitude values (mean 47 mU.ml-1, SD 3). The [Hb] had increased significantly above pre-altitude values (mean 8.8 mmol.l-1, SD 0.5) on day 2 (mean 9.1 mmol.l-1, SD 0.4) and day 7 (mean 9.4 mmol.l-1, SD 0.4) at altitude and on day 4 postaltitutde (mean 9.2 mmol.l-1, SD 0.4). The reticulocyte counts had increased significantly above pre-altitude values (mean 6%, SD 3%) on day 3 at altitude (mean 12%, SD 8%) and day 4 postaltitude (mean 10%, SD 5%). The RBC counts had increased on the 4th postaltitude day. The transferrin-iron saturation had decreased below pre-altitude values (mean 23%, SD 4%) on day 4 postaltitude (mean 14%, SD 5%) and had increased on day 11 postaltitude (mean 22%, SD 7%). There were no significant changes in MCV, MCHC, PCV, maximal oxygen uptake and maximal achieved ventilation, and heart rate pre- to postaltitude. These observations demonstrated an erythropoietic response to the altitude training which was not sufficient to increase the postaltitude maximal oxygen uptake. |
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Authors:
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T Klausen; T Mohr; U Ghisler; O J Nielsen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of applied physiology and occupational physiology Volume: 62 ISSN: 0301-5548 ISO Abbreviation: Eur J Appl Physiol Occup Physiol Publication Date: 1991 |
Date Detail:
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Created Date: 1991-09-23 Completed Date: 1991-09-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0410266 Medline TA: Eur J Appl Physiol Occup Physiol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 376-9 Citation Subset: IM; S |
Affiliation:
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Department of Clinical Physiology and Nuclear Medicine, University Hospital of Fredriksberg, Denmark. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Altitude* Erythrocyte Count Erythropoiesis* Erythropoietin / blood Hemoglobins / metabolism Humans Male Oxygen Consumption* Physical Education and Training* Reticulocytes Transferrin / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 11096-26-7/Erythropoietin; 11096-37-0/Transferrin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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