Document Detail

Maxillary sinus pathology in 119 patients--a histopathologic study.
MedLine Citation:
PMID:  15974429     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Information on histopathological changes within sinus mucosa is lacking, both in the general population, and in subjects with specific facial morphology and chronic respiratory obstruction. AIMS AND OBJECTIVES: To provide baseline data of the frequency and nature of pathological changes in the maxillary sinus in a specified group of patients. METHODS: 119 patients undergoing elective maxillary osteotomies were selected. These included patients with (70) and without (49) vertical maxillary excess (VME), and mouth and nasal breathers. The frequency and nature of the histopathological changes within the maxillary antral lining were recorded. RESULTS: Patients ranged from 13 to 47 years, with a M:F ratio of 1:2.4. The findings included congestion (95%), submucosal oedema (90%), retention cysts (26%), true polyps (4.6%) and inflammation. There was eosinophilia (68%), basement membrane thickening (28%), goblet cell hyperplasia (95%) and dystrophic calcification (59%). CONCLUSIONS: A significant degree of sinus pathology was found in this specified group of patients. This was probably due to their living in a polluted urban environment. In the presence of such widespread pathological changes and the virtual impossibility of obtaining "normal" control tissue, investigators may find it impossible to correlate maxillary sinus pathology with either facial form or breathing pattern.
Hedley Coleman; Shabnum Meer; Mario Altini; Johan Reyneke; Pieter Becker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging     Volume:  60     ISSN:  1029-4864     ISO Abbreviation:  SADJ     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-06-24     Completed Date:  2005-07-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9812497     Medline TA:  SADJ     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  140, 142-5     Citation Subset:  D    
Division of Oral Pathology, Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg.
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MeSH Terms
Basement Membrane / pathology
Calcinosis / pathology
Edema / pathology
Eosinophilia / pathology
Goblet Cells / pathology
Maxilla / abnormalities
Maxillary Sinus / pathology*
Maxillary Sinusitis / pathology
Middle Aged
Mouth Breathing / complications
Mucocele / pathology
Mucous Membrane / pathology
Paranasal Sinus Diseases / pathology*
Polyps / pathology

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