Document Detail


Mauriac syndrome in a 3-year-old boy.
MedLine Citation:
PMID:  17360304     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To report a case of Mauriac syndrome in a young child with poorly controlled type 1 diabetes mellitus. METHODS: We describe the typical features of Mauriac syndrome and review the clinical, laboratory, and ultrasound findings and follow-up results in our current patient. RESULTS: Hepatomegaly, growth impairment, and cushingoid features characterize Mauriac syndrome. Most frequently, it is seen in adolescents and young adults with a history of poor glycemic control. In our current patient, a 3-year-old boy with type 1 diabetes mellitus of 2 years' duration, Mauriac syndrome developed in the context of a disrupted social environment. His liver enzyme derangement, hepatomegaly, and growth improved once euglycemia was achieved. CONCLUSION: Although Mauriac syndrome is currently uncommon, close monitoring of children with type 1 diabetes is important to maintain optimal glycemic control and prevent such an occurrence.
Authors:
Shefali Mahesh; Robert J Karp; Salvador Castells; Jose Bernardo Q Quintos
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists     Volume:  13     ISSN:  1934-2403     ISO Abbreviation:  Endocr Pract     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2007-03-15     Completed Date:  2007-04-12     Revised Date:  2007-10-30    
Medline Journal Info:
Nlm Unique ID:  9607439     Medline TA:  Endocr Pract     Country:  United States    
Other Details:
Languages:  eng     Pagination:  63-6     Citation Subset:  IM    
Affiliation:
Department of Pediatric Nephrology, Montefiore Medical Center, Bronx, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Diabetes Mellitus, Type 1 / diagnosis*,  drug therapy*,  physiopathology
Growth Disorders / diagnosis*,  physiopathology
Hepatomegaly / diagnosis*,  physiopathology
Humans
Hyperglycemia / diagnosis,  drug therapy,  physiopathology
Hypoglycemic Agents / therapeutic use*
Insulin / therapeutic use*
Male
Syndrome
Chemical
Reg. No./Substance:
0/Hypoglycemic Agents; 11061-68-0/Insulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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