| Maturational time course of the envelope following response to amplitude-modulated acoustic signals in rats. | |
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MedLine Citation:
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PMID: 22176306 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective: The maturation pattern of the envelope following response (EFR) was described using rats as an experimental model. Design: EFRs were recorded in animals at different postnatal ages (15, 20, 25, 35, and 70 postnatal days) in response to broadband noise (BBN) and tones of 8 and 4 kHz modulated in amplitude using a continuous sweep of modulation frequencies. Responses were analysed in the 90-190 Hz modulation frequency (MF) range. Study sample: Forty individuals (eight individuals for each age bracket) were included in the present study. Results: During maturation, the MF at which the maximum amplitude was obtained (BMF, best modulation frequency) shifted to higher values when animals were stimulated with tones. At the same time, the amplitude of the response at the BMF increased. For every group of animals, the amplitude of the response continuously decreased for MFs higher than the BMF. However, less steep decreases of amplitude were obtained as animals became adults. Conclusions: These results provide normative data regarding the maturation of the EFR in rats. They provide information for the development of predictor models to estimate the temporal resolution of the auditory system during maturation. |
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Authors:
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Pavel Prado-Gutierrez; Eleina Mijares; Guillermo Savio; Mayelin Borrego; Eduardo Martínez-Montes; Alejandro Torres |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-19 |
Journal Detail:
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Title: International journal of audiology Volume: - ISSN: 1708-8186 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101140017 Medline TA: Int J Audiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Cuban Neuroscience Center , Havana , Cuba. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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