| Matrix-assisted laser desorption ionization imaging mass spectrometry in lipidomics. | |
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MedLine Citation:
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PMID: 21308368 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The relevant structural, energetics, and regulatory roles of lipids are universally acknowledged. However, the high variability of lipid species and the large differences in concentrations make unraveling the role played by the different species in metabolism a titanic task. A recently developed technique, known as imaging mass spectrometry, may shed some light on the field, as it enables precise information to be obtained on the location of lipids in tissues. A review of the state of the art of the technique is presented in this manuscript, including detailed analysis of sample-preparation steps, data handling, and the identification of the species mapped so far. |
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Authors:
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J A Fernández; B Ochoa; O Fresnedo; M T Giralt; R Rodríguez-Puertas |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-10 |
Journal Detail:
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Title: Analytical and bioanalytical chemistry Volume: - ISSN: 1618-2650 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101134327 Medline TA: Anal Bioanal Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Chemical Physics, Faculty of Science and Technology, University of the Basque Country, Bº Sarriena s/n, 48940, Leioa, Spain, josea.fernandez@ehu.es. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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