| Matrix Metalloproteinases and Descending Aortic Aneurysms: Parity, Disparity, and Switch. | |
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MedLine Citation:
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PMID: 21958052 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Central to the pathologic changes in developing aortic aneurysms are alterations in the abundance and activity of proteases, of which the most important for aneurysm production comprise the matrix metalloproteinase (MMP) family. In this review, literature demonstrating the role of MMPs in the development of aortic aneurysms is presented, with emphasis on the parity and disparity between the thoracic and abdominal aorta. Furthermore, the role of embryologic cellular origins and evidence of phenotypic switch will be addressed in terms of how this process alters MMP production during aneurysm development. (J Card Surg 2011;**:1-10). |
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Authors:
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Tom P Theruvath; Jeffrey A Jones; John S Ikonomidis |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-29 |
Journal Detail:
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Title: Journal of cardiac surgery Volume: - ISSN: 1540-8191 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8908809 Medline TA: J Card Surg Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Wiley Periodicals, Inc. |
Affiliation:
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Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina; and Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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