Document Detail


Mathematics learning disability in girls with Turner syndrome or fragile X syndrome.
MedLine Citation:
PMID:  16500739     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two studies were carried out to examine the persistence (Study 1) and characteristics (Study 2) of mathematics learning disability (MLD) in girls with Turner syndrome or fragile X during the primary school years (ages 5-9 years). In Study 1, the rate of MLD for each syndrome group exceeded the rate observed in a grade-matched comparison group, although the likelihood of MLD persisting through the primary school years was comparable for all three groups. In Study 2, formal and informal math skills were compared across the syndrome groups, a normative group, and children from the normative group who had MLD. Few differences were observed between the Turner syndrome and normative groups. Despite having rote counting and number representation skills comparable to those in the normative group, girls with fragile X had difficulty with counting rules (e.g., cardinality, number constancy). However, this difficulty did not distingush them from the MLD group. Overall, counting skills appear to distinguish the Turner syndrome and fragile X groups, suggesting that the specificity of math deficits emerges earlier for fragile X than Turner syndrome.
Authors:
Melissa M Murphy; Michèle M M Mazzocco; Gwendolyn Gerner; Anne E Henry
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2006-02-24
Journal Detail:
Title:  Brain and cognition     Volume:  61     ISSN:  0278-2626     ISO Abbreviation:  Brain Cogn     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-05-30     Completed Date:  2006-08-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8218014     Medline TA:  Brain Cogn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  195-210     Citation Subset:  IM    
Affiliation:
Johns Hopkins School of Medicine, Department of Psychiatry and Behavioral Sciences, Baltimore, MD, USA.
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Cognition Disorders / diagnosis*,  epidemiology*
Female
Fragile X Syndrome / epidemiology*
Humans
Incidence
Learning Disorders / diagnosis*,  epidemiology*
Mathematics*
Neuropsychological Tests
Prevalence
Severity of Illness Index
Turner Syndrome / epidemiology*
Grant Support
ID/Acronym/Agency:
HD R01 03461/HD/NICHD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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