|Mathematical representation of organ growth in the human embryo/fetus.|
|PMID: 7490167 Owner: NLM Status: MEDLINE|
|During human pregnancy, there is a huge increase in the total weight of the embryo/fetus from conception to term. The total growth, which is the summation of growth of the various organs and tissues that make up the organism, was analyzed in a previous paper and fitted to the Gompertz equation for growth. In the present study, allometry, the quantitative representation of the consequence of size, was utilized to describe the correlation of individual fetal organ/tissue weights with the total fetal weight. The organ/tissue weight and the total fetal weight data used in the analyses were pooled from various sources that provided data ranging from 25 days to 300 days post-conception. Allometric equations are presented for 16 embryo/fetal organs and tissues. The standard allometric equation gave adequate fits for embryo/fetal adrenal, bone, bone marrow, brain, heart, liver, pancreas, plasma, skeletal muscle, extracellular water, thymus and thyroid; but it was necessary to use a quadratic form of the allometric equation for embryo/fetal fat, kidney, lung and spleen. Parameters were also calculated for crown-to-rump and crown-to-heels for fetal lengths that occur during pregnancy.|
|R H Luecke; W D Wosilait; J F Young|
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|Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.|
|Title: International journal of bio-medical computing Volume: 39 ISSN: 0020-7101 ISO Abbreviation: Int. J. Biomed. Comput. Publication Date: 1995 Jun|
|Created Date: 1996-01-04 Completed Date: 1996-01-04 Revised Date: 2007-11-15|
Medline Journal Info:
|Nlm Unique ID: 0252005 Medline TA: Int J Biomed Comput Country: IRELAND|
|Languages: eng Pagination: 337-47 Citation Subset: IM|
|Department of Chemical Engineering, University of Missouri-Columbia 65211, USA.|
|APA/MLA Format Download EndNote Download BibTex|
Adrenal Glands / embryology
Bone Marrow / embryology
Bone and Bones / embryology
Brain / embryology
Embryonic and Fetal Development*
Fetal Heart / anatomy & histology
Kidney / embryology
Liver / embryology
Lung / embryology
Muscle, Skeletal / embryology
Pancreas / embryology
Spleen / embryology
Thymus Gland / embryology
Thyroid Gland / embryology
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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