Document Detail


Maternally derived antibodies against Bordetella pertussis antigens pertussis toxin and filamentous hemagglutinin in preterm and full term newborns.
MedLine Citation:
PMID:  19319020     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We measured IgG-anti-pertussis toxin and -IgG-anti-filamentous hemagglutinin antibody values in 43 full term and 34 preterm infants and 79 mothers. Antibody values were generally low and mean values were higher in full term than preterm infants. Transfer ratios increased with gestational age of the newborns. Based on these findings, maternal and neonatal immunization strategies should be considered to protect young infants from pertussis.
Authors:
Ulrich Heininger; Marion Riffelmann; Birgit Leineweber; Carl Heinz Wirsing von Koenig
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  28     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-28     Completed Date:  2009-07-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  443-5     Citation Subset:  IM    
Affiliation:
Division of Pediatric Infectious Diseases, University Children's Hospital, Basel, Switzerland. Ulrich.Heininger@ukbb.ch
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MeSH Terms
Descriptor/Qualifier:
Adhesins, Bacterial / immunology*
Antibodies, Bacterial / blood*
Bordetella pertussis / immunology*
Female
Humans
Immunity, Maternally-Acquired
Infant, Newborn
Infant, Premature / blood*
Pertussis Toxin / immunology*
Pregnancy
Virulence Factors, Bordetella / immunology*
Chemical
Reg. No./Substance:
0/Adhesins, Bacterial; 0/Antibodies, Bacterial; 0/Virulence Factors, Bordetella; 0/filamentous hemagglutinin adhesin, Bordetella pertussis; EC 2.4.2.31/Pertussis Toxin

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