| Maternal vitamin D status in pregnancy and adverse pregnancy outcomes in a group at high risk for pre-eclampsia. | |
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MedLine Citation:
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PMID: 21040394 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To determine in a group of pregnant women if vitamin D status, based on serum 25-hydroxyvitamin D (25OHD) concentration, was associated with a subsequent risk of pre-eclampsia or adverse pregnancy outcomes. DESIGN: Prospective cohort study. SETTING: Vancouver, British Columbia, Canada (49°N). POPULATION: Women attending a specialist antenatal clinic because of clinical or biochemical risk factors for pre-eclampsia (n = 221). METHODS: Serum 25OHD concentration measured between 10 and 20 weeks of gestation. MAIN OUTCOME MEASURES: Pre-eclampsia and composite adverse pregnancy outcomes. RESULTS: Of the women, 78% were vitamin D insufficient (25OHD <75 nmol/l) and 53% were vitamin D deficient (25OHD <50 nmol/l). There was no difference in the rates of pre-eclampsia, gestational hypertension, preterm birth or composite adverse pregnancy outcomes by 25OHD concentration. CONCLUSIONS: Vitamin D deficiency and insufficiency were common in a group of women at high risk of pre-eclampsia; however, it was not associated with subsequent risk of an adverse pregnancy outcome. |
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Authors:
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A W Shand; N Nassar; P Von Dadelszen; S M Innis; T J Green |
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Publication Detail:
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Type: Journal Article Date: 2010-10-13 |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 117 ISSN: 1471-0528 ISO Abbreviation: BJOG Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 1593-8 Citation Subset: AIM; IM |
Copyright Information:
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© 2010 The Authors Journal compilation © RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology. |
Affiliation:
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Department of Maternal Fetal Medicine, BC Women's Hospital, Vancouver, BC, Canada. awshand@yahoo.com.au |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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