Document Detail

Maternal vegan diet causing a serious infantile neurological disorder due to vitamin B12 deficiency.
MedLine Citation:
PMID:  2044594     Owner:  NLM     Status:  MEDLINE    
We present a 9-month-old exclusively breast-fed baby of a strict vegetarian mother who had excluded all animal proteins from her diet. The patient's symptoms included dystrophy, weakness, muscular atrophy, loss of tendon reflexes, psychomotor regression and haematological abnormalities. Biochemical investigations revealed severe methylmalonic aciduria and homocystinuria in the patient, slight methylmalonic aciduria in the mother and low concentrations of serum vitamin B12 in both patient and mother.
T Kühne; R Bubl; R Baumgartner
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  150     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1991 Jan 
Date Detail:
Created Date:  1991-07-17     Completed Date:  1991-07-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  205-8     Citation Subset:  IM    
University Children's Hospital Basel, Switzerland.
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MeSH Terms
Breast Feeding*
Diet, Vegetarian / adverse effects*
Homocysteine / blood
Methionine / blood
Methylmalonic Acid / urine
Milk, Human / chemistry
Nervous System Diseases / etiology*
Vitamin B 12 / analysis,  blood
Vitamin B 12 Deficiency / blood,  diagnosis,  etiology*
Reg. No./Substance:
454-28-4/Homocysteine; 516-05-2/Methylmalonic Acid; 63-68-3/Methionine; 68-19-9/Vitamin B 12

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