Document Detail

Maternal ulcerative colitis and fetal brain injury: long-term neurologic outcome.
MedLine Citation:
PMID:  18006959     Owner:  NLM     Status:  MEDLINE    
Two maternal-fetal case presentations illustrate the possible association of active maternal ulcerative colitis during pregnancy and fetal brain injury resulting in long-term neurological sequelae. Thromboembolic complications may occur in the fetus based on similar mechanisms for stroke in children and adults with active inflammatory bowel disease. Identification of thrombophilia in the pregnant woman with active ulcerative colitis may better explain a pathophysiologic mechanism for long-term neurological morbidity in offspring.
Mark S Scher
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  22     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-16     Completed Date:  2008-02-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  1293-6     Citation Subset:  IM    
Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA.
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MeSH Terms
Brain Injuries / etiology*
Child, Preschool
Colitis, Ulcerative / complications*
Fetal Diseases / etiology*
Pregnancy Complications*

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