Document Detail

Maternal thyroid disease: a risk factor for newborn encephalopathy in term infants.
MedLine Citation:
PMID:  10847239     Owner:  NLM     Status:  MEDLINE    
Two previously published studies of term newborn encephalopathy showed that maternal thyroid disease to be a risk factor. From these studies we identified 13 case and three control mothers with thyroid disease and investigated them further. The majority of affected case mothers had idiopathic or autoimmune hypothyroidism. Compared with control mothers, case mothers had fewer thyroid function tests in pregnancy, were more likely to remain on the same dose of medication throughout pregnancy and to have experienced other pregnancy complications. The association between maternal thyroid disease and encephalopathy may be the result of a series of different causal pathways, some of which are suggested by our data.
N Badawi; J J Kurinczuk; C L Mackenzie; J M Keogh; P R Burton; P J Pemberton; F J Stanley
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  107     ISSN:  1470-0328     ISO Abbreviation:  BJOG     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-07-03     Completed Date:  2000-07-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  798-801     Citation Subset:  AIM; IM    
TVW Telethon Institute for Child Health Research, Western Australia.
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MeSH Terms
Brain Diseases / embryology*
Infant, Newborn
Infant, Newborn, Diseases / embryology*
Pregnancy Complications*
Prospective Studies
Risk Factors
Comment In:
BJOG. 2001 Jul;108(7):769-70   [PMID:  11467710 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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