Document Detail

Maternal stress in pregnancy: considerations for fetal development.
MedLine Citation:
PMID:  22794531     Owner:  NLM     Status:  MEDLINE    
There is significant current interest in the degree to which prenatal exposures, including maternal psychological factors, influence child outcomes. Studies that detect an association between prenatal maternal psychological distress and child developmental outcomes are subject to a number of interpretative challenges in the inference of causality. Some of these are common to many types of prenatal exposures that must necessarily rely on observational designs. Such challenges include the correlation between prenatal and postnatal exposures and the potential role of other sources of shared influence, such as genetic factors. Others are more specific to this area of research. These include confounding between maternal report of child outcomes and the maternal psychological attributes under study, difficulties in distinguishing maternal stress from more ubiquitous aspects of maternal personality, and the lack of association between cortisol and measures of maternal psychological stress. This article considers these methodological issues and offers an additional methodology focused on fetal neurobehavior for discerning potential mechanisms that may mediate associations between maternal psychological functioning and the developing fetal nervous system.
Janet A Dipietro
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The Journal of adolescent health : official publication of the Society for Adolescent Medicine     Volume:  51     ISSN:  1879-1972     ISO Abbreviation:  J Adolesc Health     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-16     Completed Date:  2012-12-20     Revised Date:  2013-08-12    
Medline Journal Info:
Nlm Unique ID:  9102136     Medline TA:  J Adolesc Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S3-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA.
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MeSH Terms
Fetal Development*
Infant, Newborn
Maternal-Fetal Relations
Pregnancy / psychology
Pregnancy Complications / psychology*
Pregnancy Outcome
Prenatal Care / methods
Prenatal Exposure Delayed Effects*
Stress, Psychological*
Grant Support
NICHD 2 R01 HD27592-18//PHS HHS; R01 HD027592/HD/NICHD NIH HHS

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