Document Detail


Maternal smoking and partial exchange transfusion for neonatal polycythemia.
MedLine Citation:
PMID:  12442223     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to determine if maternal smoking was associated with an increased need for partial exchange transfusion for symptomatic polycythemia in term neonates. The study population consisted of 8,961 term neonates, of whom 28.7% were categorized as babies born to mothers who smoked. The incidence of partial exchange transfusion was determined in neonates whose mothers smoked and in neonates of nonsmokers. Partial exchange transfusion was performed in 41 neonates of mothers who smoked (1.59%; n = 2,572) versus 41 neonates of nonsmokers (0.64%; n = 6,389) ( p = 0.000). In babies requiring a partial exchange transfusion birth weights were 2,908 +/- 659 g (smokers) versus 3,474 +/- 770 g, (nonsmokers) ( p <0.001) and the babies born to mothers who smoked were 9 times more likely to be small-for-gestational age (SGA) and 5 times less likely to be large-for-gestational age (LGA). Term neonates of mothers who smoke during pregnancy require a partial exchange transfusion for neonatal polycythemia approximately two and a half times as often as neonates of mothers who do not smoke.
Authors:
Feyisola O Awonusonu; Thomas H Pauly; Alastair A Hutchison
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  19     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-11-20     Completed Date:  2003-02-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  349-54     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Kentucky, Lexington, Kentucky, USA.
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MeSH Terms
Descriptor/Qualifier:
Case-Control Studies
Chi-Square Distribution
Confidence Intervals
Exchange Transfusion, Whole Blood
Female
Follow-Up Studies
Humans
Incidence
Infant, Newborn
Maternal Exposure / adverse effects
Maternal-Fetal Exchange
Polycythemia / congenital*,  epidemiology,  therapy*
Pregnancy
Probability
Retrospective Studies
Risk Assessment
Smoking / adverse effects*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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