Document Detail


Maternal smoking during pregnancy increases the risk of postnatal infections in preterm neonates.
MedLine Citation:
PMID:  18212492     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Maternal smoking during pregnancy is known to be associated with perinatal complications such as preterm delivery, low birth weight, and sudden infant death syndrome. OBJECTIVE: The purpose of this study was to evaluate the influence of smoking during pregnancy on the risk of postnatal infections in preterm neonates. METHOD: We examined 80 preterm infants (gestational age 24-36 weeks), of whom 40% had been exposed to tobacco smoking during pregnancy. RESULTS: Infections occurred in 31 infants. Gestational age and maternal smoking had a significant effect on the occurrence of infections (p < 0.001 and p = 0.015, respectively). An increase in maternal tobacco consumption by 10 cigarettes/day showed an odds ratio of 2.7 (95% confidence interval 1.1-6.4) for occurrence of infections. CONCLUSIONS: A significant association between maternal use of tobacco and the occurrence of infections in preterm neonates was found. Thus, campaigns about the damaging effects of tobacco are still warranted.
Authors:
Dorthe Lisbeth Jeppesen; Susanne Dam Nielsen; Annette Kjaer Ersbøll; Niels Henrik Valerius
Publication Detail:
Type:  Journal Article     Date:  2008-01-22
Journal Detail:
Title:  Neonatology     Volume:  94     ISSN:  1661-7819     ISO Abbreviation:  -     Publication Date:  2008  
Date Detail:
Created Date:  2008-08-07     Completed Date:  2008-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101286577     Medline TA:  Neonatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  75-8     Citation Subset:  IM    
Copyright Information:
(c) 2008 S. Karger AG, Basel
Affiliation:
Department of Paediatrics, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Denmark / epidemiology
Female
Gestational Age
Humans
Infant, Newborn
Infant, Newborn, Diseases / epidemiology,  etiology*
Infant, Premature*
Infection / epidemiology,  etiology*
Maternal Exposure*
Pregnancy
Prospective Studies
Risk Factors
Smoking / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical value of the malnutrition-inflammation-atherosclerosis syndrome for long-term prediction of...
Next Document:  Valproic acid and CEBPalpha-mediated regulation of adipokine gene expression in hypothalamic neurons...