Document Detail


Maternal serum screening for Down syndrome: are women's perceptions changing?
MedLine Citation:
PMID:  17378818     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To document trends in serum screening for Down's syndrome. BACKGROUND: Trends in the uptake of serum screening for Down syndrome have not been documented in a UK population. DESIGN: A retrospective review of the rate of uptake in a unit that has offered serum screening for Down syndrome to all pregnant women. SETTING: A large north of England hospital that has offered universal Down syndrome screening using the 'triple test' since 1992. PATIENTS: A total of 47,998 women who booked for antenatal care. MAIN OUTCOME MEASURES: Uptake of serum screening for Down syndrome. METHODS: The results of the screening programme were contemporaneously recorded on a computer database, and the study team accessed the data. RESULTS: There was a significant reduction in the uptake of serum screening for Down syndrome from a maximum of 82.6% in 1993 to 41.4% in 2005. There was a significant but small trend upwards in the age of women accepting screening and also a significant trend in the increase in the screen-positive rates. CONCLUSIONS: The reduction in uptake of Down syndrome screening over the past 13 years must be taken into account when planning a screening programme. Other units should be encouraged to review their rate of uptake to determine if our data are representative of a wider trend.
Authors:
M Gidiri; J McFarlane; S Holding; Sw Lindow
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  114     ISSN:  1470-0328     ISO Abbreviation:  BJOG     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-23     Completed Date:  2007-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  458-61     Citation Subset:  AIM; IM    
Affiliation:
Academic Department of Obstetrics and Gynaecology, Women and Children's Hospital, Hull Royal Infirmary, Hull, UK. fmgidiri@doctors.org.uk
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MeSH Terms
Descriptor/Qualifier:
Adult
Attitude to Health*
Down Syndrome / diagnosis*,  psychology
Female
Humans
Maternal Age
Patient Acceptance of Health Care
Perception
Pregnancy
Prenatal Diagnosis / psychology*,  trends
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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