| Maternal serum mannose-binding lectin in severe preeclampsia. | |
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MedLine Citation:
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PMID: 18754287 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: We aimed to investigate the level of serum mannose-binding lectin (MBL) in severe preeclamptic patients, women with uncomplicated pregnancies, and healthy reproductive-age females and its impact on gestational age at delivery and birth weight. METHODS: Serum MBL levels were measured in 27 severe preeclampsia patients (Group 1), 27 patients with uncomplicated pregnancies (Group 2), and 25 healthy reproductive-age women (Group 3). RESULTS: The mean serum MBL was significantly higher (p < or = 0.05) in Group 1 than in Groups 2 and 3, while the levels in Groups 2 and 3 did not significantly differ. The mean gestational age at delivery and mean birth weight were significantly lower in Group 1. In Group 1, serum MBL was negatively correlated (p < or = 0.05) with the gestational age at delivery and birth weight. CONCLUSION: Serum MBL increased in preeclampsia and was negatively correlated with the gestational age at birth and birth weight, indicating an underlying immunopathogenesis. |
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Authors:
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N Celik; H Ozan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical and experimental obstetrics & gynecology Volume: 35 ISSN: 0390-6663 ISO Abbreviation: Clin Exp Obstet Gynecol Publication Date: 2008 |
Date Detail:
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Created Date: 2008-08-29 Completed Date: 2008-11-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7802110 Medline TA: Clin Exp Obstet Gynecol Country: Italy |
Other Details:
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Languages: eng Pagination: 179-82 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Uludag University Medical Faculty, Bursa, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Weight Case-Control Studies Female Gestational Age Humans Infant, Newborn Male Mannose-Binding Lectin / blood* Pre-Eclampsia / blood* Pregnancy |
| Chemical | |
Reg. No./Substance:
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0/Mannose-Binding Lectin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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