Document Detail

Maternal serum alpha-fetoprotein levels between 13 and 24 weeks' gestation.
MedLine Citation:
PMID:  7531609     Owner:  NLM     Status:  MEDLINE    
Maternal serum alpha-fetoprotein (MSAFP) screening has been widely used and proven valuable in the prediction of a variety of fetal disorders. Any laboratory intending to provide MSAFP screening needs to establish its own reference data. In order to establish a normal MSAFP median value at our own laboratory, 5256 samples of MSAFP were collected from uncomplicated, singleton pregnant women between 13 and 24 weeks' gestation. The MSAFP median levels steadily rise with advancing gestation about 16% per gestational week in average. There were 0.17% and 4.4% of the pregnancies with serum AFP levels less than 0.25 multiple of the median (MoM) and 0.5 MoM respectively, and 4.22% and 1.66% with serum levels above 2.0 MoM and 2.5 MoM. Accurate and satisfactory interpretation of MSAFP screening should be emphasized in the establishment of a well-developed normal median value.
J J Hsu; T H Chiu; K C Chen; J D Liou; T T Hseih; Y K Soong
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital     Volume:  17     ISSN:  -     ISO Abbreviation:  Changgeng Yi Xue Za Zhi     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-03-14     Completed Date:  1995-03-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9809559     Medline TA:  Changgeng Yi Xue Za Zhi     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  309-15     Citation Subset:  IM    
Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.
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MeSH Terms
Pregnancy / blood*
Pregnancy Trimester, Second
Reference Values
alpha-Fetoproteins / metabolism*
Reg. No./Substance:

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