Document Detail

Maternal serum alpha-fetoprotein levels in multiple pregnancy.
MedLine Citation:
PMID:  47778     Owner:  NLM     Status:  MEDLINE    
Maternal serum alpha-fetoprotein (AFP) levels were higher in 10 twin pregnancies and one triplet pregnancy than in 22 control singleton pregnancies matched for maternal age, parity, and the time of gestation at which the serum sample was taken. In twin pregnancies the average AFP levels were double those found in singleton pregnancies and the level in the triplet pregnancy was even higher. Raised maternal serum AFP values due to multiple pregnancy should not cause unnecessary amniocentesis in the diagnosis of anencephaly or spina bifida if an ultrasound investigation is routinely performed first.
N Wald; S Barker; R Peto; D J Brock; J Bonnar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  1     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1975 Mar 
Date Detail:
Created Date:  1975-08-07     Completed Date:  1975-08-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  651-2     Citation Subset:  AIM; IM    
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MeSH Terms
Anencephaly / diagnosis
Fetal Proteins / analysis*
Maternal Age
Pregnancy, Multiple*
Spinal Dysraphism / diagnosis
Time Factors
alpha-Fetoproteins / analysis*
Reg. No./Substance:
0/Fetal Proteins; 0/alpha-Fetoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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