Document Detail


Maternal serum alpha-fetoprotein levels in multiple pregnancy.
MedLine Citation:
PMID:  47778     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Maternal serum alpha-fetoprotein (AFP) levels were higher in 10 twin pregnancies and one triplet pregnancy than in 22 control singleton pregnancies matched for maternal age, parity, and the time of gestation at which the serum sample was taken. In twin pregnancies the average AFP levels were double those found in singleton pregnancies and the level in the triplet pregnancy was even higher. Raised maternal serum AFP values due to multiple pregnancy should not cause unnecessary amniocentesis in the diagnosis of anencephaly or spina bifida if an ultrasound investigation is routinely performed first.
Authors:
N Wald; S Barker; R Peto; D J Brock; J Bonnar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  1     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1975 Mar 
Date Detail:
Created Date:  1975-08-07     Completed Date:  1975-08-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  651-2     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Anencephaly / diagnosis
Female
Fetal Proteins / analysis*
Humans
Maternal Age
Parity
Pregnancy
Pregnancy, Multiple*
Radioimmunoassay
Spinal Dysraphism / diagnosis
Time Factors
Triplets
Twins
alpha-Fetoproteins / analysis*
Chemical
Reg. No./Substance:
0/Fetal Proteins; 0/alpha-Fetoproteins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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