| Maternal sepsis: epidemiology, etiology and outcome. | |
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MedLine Citation:
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PMID: 20375891 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE OF REVIEW: Sepsis is a major cause of maternal death worldwide. Little is known on the incidence of severe maternal morbidity related to sepsis. In this review, we focus on new findings concerning epidemiology, etiology and outcome of maternal sepsis in low-income as well as high-income countries. RECENT FINDINGS: It is estimated that puerperal sepsis causes at least 75,000 maternal deaths every year, mostly in low-income countries. Studies from high-income countries report incidence of maternal morbidity due to sepsis of 0.1-0.6 per 1000 deliveries. The causative microorganisms are generally polymicrobial with beta-haemolytic streptococci group A (GAS) often being the cause of severe cases of puerperal fever. The single most important risk factor for postpartum infection seems to be caesarean section, and prophylactic antibiotics during the procedure substantially reduce the infection risk. Improvements in service provision as promoted through the Surviving Sepsis Campaign can reduce the overall risk of mortality and morbidity from maternal sepsis in high-income as well as in low-income countries. SUMMARY: Maternal sepsis is an infrequent, but important complication of pregnancy, childbirth and puerperium, resulting in significant maternal morbidity and mortality worldwide. Improved outcome is possible through improved service provision. |
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Authors:
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Jeroen van Dillen; Joost Zwart; Joke Schutte; Jos van Roosmalen |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current opinion in infectious diseases Volume: 23 ISSN: 1473-6527 ISO Abbreviation: Curr. Opin. Infect. Dis. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-04-21 Completed Date: 2010-07-12 Revised Date: 2012-01-31 |
Medline Journal Info:
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Nlm Unique ID: 8809878 Medline TA: Curr Opin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 249-54 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Reinier de Graaf Gasthuis, Delft, The Netherlands. j.j.m.van_roosmalen@lumc.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Pregnancy Pregnancy Complications, Infectious / epidemiology*, etiology*, mortality Puerperal Infection / epidemiology*, etiology*, mortality Sepsis / epidemiology*, etiology*, mortality Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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