Document Detail


Maternal selenium levels and sudden infant death syndrome (SIDS).
MedLine Citation:
PMID:  8958364     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The possibility is tested that low anti-oxidant status and/or low levels of selenium (Se) might predispose to Sudden Infant Death Syndrome (SIDS). AIM: This study was undertaken to collect evidence on the Se status of pregnant and non-pregnant women and newborn babies and to establish whether babies who later died of cot death had significantly divergent levels of blood Se at birth. METHODOLOGY: Aliquots of blood were collected from all newly pregnant mothers in Tasmania and from the cords of all newborn babies. These were analysed for Se and glutathione peroxidase (GPx) content and compared by season and with non-pregnant, age standardised blood donors in three areas of Tasmania and three mainland Australian States. RESULTS: Cot death babies' cordbloods were not significantly different in Se or GPx-status, in this small sample, from those of other babies, nor was a seasonal variation in these parameters demonstrated among 390 randomly selected Tasmanian mothers. Mothers-to-be showed a decrease in enzyme levels during pregnancy and Tasmanian blood donors had significantly lower levels than donors from other States. CONCLUSION: While no evidence can safely be drawn about a relationship between Se or GPx-status and SIDS, this study provides base level measures for populations showing that Tasmanian residents have low levels of these anti-oxidants.
Authors:
N D McGlashan; S J Cook; W Melrose; P L Martin; E Chelkowska; R J von Witt
Related Documents :
12040254 - Infanticide: is its incidence among postneonatal infant deaths increasing?: an 18-year ...
11223274 - Apnoea of prematurity and arousal from sleep.
10426174 - Interactions of infectious symptoms and modifiable risk factors in sudden infant death ...
15155864 - Role of virus-induced myocardial affections in sudden infant death syndrome: a prospect...
12378194 - Why are babies getting bigger? temporal trends in fetal growth and its determinants.
18281354 - The impact of maternal hiv status on infant feeding patterns in nakuru, kenya.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Australian and New Zealand journal of medicine     Volume:  26     ISSN:  0004-8291     ISO Abbreviation:  Aust N Z J Med     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1997-03-25     Completed Date:  1997-03-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1264322     Medline TA:  Aust N Z J Med     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  677-82     Citation Subset:  IM    
Affiliation:
Department of Geography and Environmental Studies, University of Tasmania, Hobart.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Australia / epidemiology
Blood Donors
Female
Fetal Blood / chemistry
Glutathione Peroxidase / blood
Humans
Infant, Newborn
Pregnancy / blood*
Random Allocation
Selenium / blood*
Sudden Infant Death / epidemiology,  etiology*
Chemical
Reg. No./Substance:
7782-49-2/Selenium; EC 1.11.1.9/Glutathione Peroxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Adult asthma and gastro-oesophageal reflux: the effects of omeprazole therapy on asthma.
Next Document:  Rheumatic manifestations of the myelodysplastic syndromes: a comparative study.