| Maternal salivary cortisol differs by fetal sex during the second half of pregnancy. | |
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MedLine Citation:
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PMID: 20940089 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Maternal salivary cortisol was measured at weekly intervals from 24 to 38 weeks gestation. The total sample consisted of 120 women enrolled in staggered intervals in such a way as to generate weekly measures of salivary cortisol during the latter half of pregnancy. Hierarchical linear modeling revealed the expected increase in unbound maternal cortisol during this period, with a slight deceleration in rate of increase at 33 weeks gestation. Women carrying male fetuses had higher levels of salivary cortisol initially as compared to women carrying female fetuses; at 30 weeks gestation there was cross-over such that higher maternal cortisol was observed in women carrying female fetuses beyond this time and through term. Results highlight the importance of considering fetal sex as a moderator of contemporaneous and predictive associations between maternal cortisol and prenatal or postnatal development. |
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Authors:
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Janet A DiPietro; Kathleen A Costigan; Katie T Kivlighan; Ping Chen; Mark L Laudenslager |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Psychoneuroendocrinology Volume: 36 ISSN: 1873-3360 ISO Abbreviation: Psychoneuroendocrinology Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-03-04 Completed Date: 2011-06-22 Revised Date: 2012-05-02 |
Medline Journal Info:
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Nlm Unique ID: 7612148 Medline TA: Psychoneuroendocrinology Country: England |
Other Details:
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Languages: eng Pagination: 588-91 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Population, Family & Reproductive Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., W1033, Baltimore, MD 21205, USA. jdipietr@jhsph.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cohort Studies Female Fetus / physiology* Gestational Age Humans Hydrocortisone / analysis, metabolism* Longitudinal Studies Male Mothers Pregnancy / metabolism Pregnancy Trimester, Second / metabolism*, physiology Pregnancy Trimester, Third / metabolism*, physiology Saliva / chemistry, metabolism* Sex Characteristics* |
| Grant Support | |
ID/Acronym/Agency:
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R01 HD027592-20/HD/NICHD NIH HHS; R01 HD27592/HD/NICHD NIH HHS; R56 HD027592-17/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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