Document Detail

Maternal risk factors for fetal and neonatal brain damage.
MedLine Citation:
PMID:  11275644     Owner:  NLM     Status:  MEDLINE    
Prematurity is probably the major factor associated with brain damage in newborns. Our growing knowledge of the biochemical mechanisms leading to the onset of labour at term allows the biochemical correlates of the epidemiological risk factors for prematurity to be understood. Infection is the major cause of early preterm labour and is now recognised to be a major cause of fetal cerebral damage leading to cerebral palsy. Only some 5% of cerebral palsy is due to intrapartum asphyxia at term. This may occur due to an obstetric catastrophe or through inadequate placental function leading to chronic intrapartum asphyxia.
V Terzidou; P Bennett
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Biology of the neonate     Volume:  79     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  2001  
Date Detail:
Created Date:  2001-03-29     Completed Date:  2001-07-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  157-62     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Institute of Reproductive and Developmental Biology, Hammersmith Hospital, Imperial College School of Medicine, London, UK.
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MeSH Terms
Birth Injuries*
Brain Diseases / etiology*
Cerebral Palsy / etiology
Fetal Diseases / etiology*
Hypertension / complications
Infant, Newborn
Infection / complications
Obstetric Labor, Premature / etiology
Pregnancy Complications, Cardiovascular
Pregnancy, Multiple
Risk Factors
Stress, Physiological / complications
Uterine Cervical Incompetence / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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