Document Detail

Maternal renal artery blood flow velocimetry in normal and hypertensive pregnancies.
MedLine Citation:
PMID:  8906004     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate the effect of normal pregnancy and hypertensive disorders of pregnancy on the maternal renal artery Doppler blood flow velocity indices. METHODS: The patient material consisted of 30 normal pregnant women, 29 women with pregnancy induced hypertension, 43 women with preeclampsia and 22 pregnant women with chronic hypertension. Blood flow velocities in the segmental renal arteries from the right kidney were analysed by pulsed and color Doppler. The systolic/diastolic (s.d.) ratio, resistance index (RI) and pulsatility index (PI) were used for Doppler waveform analysis. RESULTS: In all of the groups of hypertensive pregnant women renal artery Doppler indices were significantly lower compared to the normal pregnant women group. There was a significant negative relationship between renal artery PI and mean arterial pressure in the preeclampsia group and in the chronic hypertension group. CONCLUSION: The present results demonstrate that the mechanism of renal autoregulation in preeclampsia might be altered, leaving glomerulus unprotected from increased blood pressure. It seems that the concept of renal vasoconstriction in preeclampsia might be disputed and needs further investigation.
M Kublickas; N O Lunell; H Nisell; M Westgren
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  75     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1996-12-03     Completed Date:  1996-12-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  715-9     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Karolinska Institutet, Huddinge University Hospital, Sweden.
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MeSH Terms
Diastole / physiology
Hypertension / physiopathology*
Pre-Eclampsia / physiopathology*
Pregnancy Complications, Cardiovascular / physiopathology*
Renal Artery / physiopathology*
Systole / physiology
Ultrasonography, Doppler, Color*
Ultrasonography, Doppler, Pulsed*
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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