Document Detail

Maternal recall of pregnancy history: accuracy and bias in schizophrenia research.
MedLine Citation:
PMID:  10885635     Owner:  NLM     Status:  MEDLINE    
Most investigations that report a positive association between obstetric complications and schizophrenia have been case-control studies that are often based on long-term maternal recall of events during pregnancy. We tested the hypothesis that mothers of adult offspring with schizophrenia or other psychoses systematically overreport obstetric complications compared with mothers of unaffected offspring. Subjects were selected from the New England cohorts of the National Collaborative Perinatal Project, a large prospective cohort with well-documented records of pregnancy and delivery. Mothers of 39 offspring with psychosis and 39 control offspring were recontacted and completed a structured interview regarding their pregnancy history. Accuracy of maternal recall varied greatly in relation to the type of pregnancy event, and recall was inaccurate for many specific events. For the control sample only, maternal recall of the total number of complications corresponded closely to chart information. Contrary to the study hypothesis, mothers of offspring with psychosis report fewer complications than indicated in their obstetric records, with no evidence of positive recall bias. These results suggest that previous reports of a positive association between obstetric complications and schizophrenia are not likely to have resulted from biased maternal recall.
S L Buka; J M Goldstein; L J Seidman; M T Tsuang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Schizophrenia bulletin     Volume:  26     ISSN:  0586-7614     ISO Abbreviation:  Schizophr Bull     Publication Date:  2000  
Date Detail:
Created Date:  2000-11-03     Completed Date:  2000-11-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0236760     Medline TA:  Schizophr Bull     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  335-50     Citation Subset:  IM    
Department of Maternal and Child Health, Harvard School of Public Health, Boston, MA 02115, USA.
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MeSH Terms
Bias (Epidemiology)
Birth Injuries / complications*,  epidemiology
Child, Preschool
Cohort Studies
Maternal Welfare
Mental Recall*
Pregnancy Complications / epidemiology*
Reproducibility of Results
Risk Assessment
Schizophrenia / etiology*

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