Document Detail

Maternal racial origin and adverse pregnancy outcomes: a cohort study.
MedLine Citation:
PMID:  23023978     Owner:  NLM     Status:  Publisher    
Objective: The aim of this study was to examine the association between maternal racial origin and a wide range of adverse pregnancy outcomes after adjustment for confounding factors in obstetric history and maternal characteristics. Methods: This was a prospective screening study for adverse pregnancy outcomes in women with singleton pregnancies attending the first routine hospital visit at 11(+0) -13(+6) weeks of gestation. Data on maternal characteristics, medical and obstetric history were collected and pregnancy outcomes ascertained. Regression analysis was performed to examine the association between racial origin and adverse pregnancy outcomes including pre-eclampsia (PE), gestational hypertension (GH), gestational diabetes mellitus (GDM), preterm delivery (PTD), small for gestational age (SGA), large for gestational age (LGA), miscarriage, stillbirth, elective and emergency Cesarean section (CS). Results: The study population included 76,158 singleton pregnancies with a live fetus at 11(+0) -13(+6) weeks. In addition to maternal characteristics and obstetric history Afro-Caribbean racial origin was associated with increased risk for miscarriage, stillbirth, PE, GH, spontaneous PTD, GDM, SGA and CS. In women of South Asian racial origin there was increased risk for PE, GDM, SGA and CS and East Asian race contributerd to the prediction of GDM and SGA. Conclusion: Maternal racial origin should be combined with other maternal characteristics and obstetric history when calculating an individualised adjusted risk for adverse pregnancy complications. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.
Asma Khalil; Juliana Rezende; Ranjit Akolekar; Argyro Syngelaki; Kypros H Nicolaides
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-1
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  -     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.
Department of Fetal Medicine, Institute for Women's Health, University College London Hospitals, London, UK.
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