Document Detail


Maternal programming in asthma and allergy.
MedLine Citation:
PMID:  9988445     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There has been increasing interest in the possibility that the mother has an important role to play in influencing the development of fetal and infant immune responses to allergens during gestation. This finding, by several groups, of specific immune responses of infants at birth to individual trigger factors associated with an underlying immaturity of cytokine production, is intriguing in the light of the development of subsequent allergic disease. The interactions between mother, placenta and fetus are now forming a focus for ongoing research and may be a potential target for intervention aimed at preventing allergic asthma.
Authors:
J A Warner; C A Jones; T J Williams; J O Warner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology     Volume:  28 Suppl 5     ISSN:  0954-7894     ISO Abbreviation:  Clin. Exp. Allergy     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-04-23     Completed Date:  1999-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8906443     Medline TA:  Clin Exp Allergy     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  35-8; discussion 50-1     Citation Subset:  IM    
Affiliation:
Child Health, University of Southampton, UK.
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MeSH Terms
Descriptor/Qualifier:
Allergens / immunology
Animals
Asthma / immunology*
Cytokines / biosynthesis
Female
Fetus / immunology*
Humans
Hypersensitivity / immunology*
Infant, Newborn
Maternal Exposure
Maternal-Fetal Exchange / immunology*
Mice
Pregnancy
Chemical
Reg. No./Substance:
0/Allergens; 0/Cytokines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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