| Maternal pregnancy-related hypertension and risk for hypertension in offspring later in life. | |
| | |
MedLine Citation:
|
PMID: 20859149 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To estimate the association between maternal pregnancy-related hypertension and offspring hypertension later in life in a birth cohort from New England. METHODS: Covariate and exposure data were collected between 1959 and 1966 through the Collaborative Perinatal Project. Follow-up information was obtained through the New England Family Study between 2001 and 2004, when study participants were between 34 and 44 years old. The study population consisted of 1,556 individuals. Participants who reported having hypertension diagnosed at least once were considered to have hypertension. Logistic regression was used to estimate the association between maternal pregnancy-related hypertension and offspring hypertension later in life. Results were adjusted for sex, maternal race, maternal body mass index, maternal socioeconomic status, maternal diabetes, and twin pregnancy. RESULTS: Maternal pregnancy-related hypertension was associated with an increased risk of being prescribed antihypertensives compared with never having hypertension diagnosed (from 8.8% to 17.4%; adjusted odds ratio 1.88, 95% confidence interval 1.00-3.55). The association was not attenuated after adjustment for birth weight or preterm delivery. After excluding offspring of women who reported hypertension during pregnancy only, this association increased to an adjusted odds ratio of 1.97 (95% confidence interval 1.04-3.72). CONCLUSION: In a birth cohort from New England, maternal pregnancy-related hypertension was associated with hypertension in offspring later in life. LEVEL OF EVIDENCE: II. |
| | |
Authors:
|
Kristin Palmsten; Stephen L Buka; Karin B Michels |
Related Documents
:
|
11489149 - Risks of hypertensive disorders in the second pregnancy. 8116519 - Preeclampsia: progress and puzzle. 15738029 - Late first-trimester placental disruption and subsequent gestational hypertension/preec... 17240239 - Concentration of circulating endothelial progenitor cells (epc) in normal pregnancy and... 18395679 - Pathophysiology of hypertension in response to placental ischemia during pregnancy: a c... 61439 - Fetal outcome in trial of antihypertensive treatment in pregnancy. 15804869 - Loupe-assisted modified one-layer vasovasostomy. 11770969 - Clinical manifestations of sinonasal pathology during pregnancy. 7140649 - The bioassay of bovine placental lactogen. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Obstetrics and gynecology Volume: 116 ISSN: 1873-233X ISO Abbreviation: Obstet Gynecol Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-22 Completed Date: 2010-10-22 Revised Date: 2013-02-19 |
Medline Journal Info:
|
Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 858-64 Citation Subset: AIM; IM |
Affiliation:
|
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Confounding Factors (Epidemiology) Female Humans Hypertension / epidemiology* Hypertension, Pregnancy-Induced / epidemiology* Logistic Models New England / epidemiology Pre-Eclampsia / epidemiology Pregnancy Prenatal Exposure Delayed Effects / epidemiology* Risk Assessment Risk Factors Young Adult |
| Grant Support | |
ID/Acronym/Agency:
|
AG023397/AG/NIA NIH HHS; P50 CA084719/CA/NCI NIH HHS; P50 CA084719/CA/NCI NIH HHS; R01 AG023397/AG/NIA NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Childhood Cardiac Function After Severe Maternal Red Cell Isoimmunization.
Next Document: Tranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trial.