Document Detail


Maternal predictors of perinatal mortality: the role of birthweight.
MedLine Citation:
PMID:  10405851     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Many maternal characteristics increase the risk for perinatal death. To locate potential sites for intervention, it is important to identify these risk factors and examine how much of the excess mortality is explained by infants' low birthweight. METHODS: Data on all newborns in Finland born between 1991 and 1993 (N = 199,291, of which 1461 were perinatal deaths) were obtained from the Medical Birth Register. Logistic regression analysis was used to adjust for background variables, both including and excluding infants' birthweight. The percentage reduction in odds ratios after adjustment for infants' birthweight was used to estimate the contribution of infants' low birthweight to the excess mortality. RESULTS: After adjusting confounding factors, increased risk for perinatal death was found for eight maternal characteristics. In the following the increased risk is given as odds ratios and the proportions of the excess mortality explained by infants' low birthweight are in parentheses: in-vitro fertilization 4.12 (> 100%); earlier stillbirth 3.43 (87%); higher maternal age, from 1.21 to 3.08 (38-99%); maternal diabetes 2.87 (50%); lower socioeconomic status, from 1.30 to 1.70 (27-44%); smoking during pregnancy 1.45 (> 100%); single mother 1.44 (50%); first birth 1.36 (75%). CONCLUSIONS: Excess mortality due to maternal risk factors occurred mainly through their tendency to cause low birthweight. However, the excess mortality associated with low socioeconomic status, single motherhood, and diabetes was mediated by other mechanisms in addition to low birthweight.
Authors:
E Forssas; M Gissler; M Sihvonen; E Hemminki
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of epidemiology     Volume:  28     ISSN:  0300-5771     ISO Abbreviation:  Int J Epidemiol     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-07-29     Completed Date:  1999-07-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802871     Medline TA:  Int J Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  475-8     Citation Subset:  IM; J    
Affiliation:
National Research and Development Centre for Welfare and Health, Health Services Research Unit, Helsinki, Finland. erja.forssas@stakes.fi
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MeSH Terms
Descriptor/Qualifier:
Adult
Birth Weight*
Confidence Intervals
Confounding Factors (Epidemiology)
Female
Finland / epidemiology
Humans
Infant Mortality*
Infant, Newborn
Logistic Models
Marital Status
Maternal Age
Odds Ratio
Pregnancy
Pregnancy in Diabetics
Prognosis
Risk Factors
Socioeconomic Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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