Document Detail

Maternal plasma glucose levels and Doppler flow velocity waveforms in cerebral arteries of growth-retarded fetuses.
MedLine Citation:
PMID:  7959325     Owner:  NLM     Status:  MEDLINE    
Doppler flow studies of the intracranial internal carotid artery and middle cerebral artery performed in 17 women at 30-36 weeks of gestation, referred for evaluation of small for gestational age fetuses, resulted in abnormally low pulsatility index values (below 2 SD). These patients were investigated when fasting and 1 h after a 100-gram glucose load. Increase of 20 ml/dl or more was followed by elevation of the mean pulsatility index in the internal carotid artery from 1.03 +/- 0.09 to 1.44 +/- 0.22 (p < 0.001), and in the middle cerebral artery from 1.12 +/- 0.16 to 1.83 +/- 0.24 (p < 0.001). Pulsatility index values returned to normal (within 2 SD for gestational age) in 15 of the subjects investigated after glucose load. These findings suggest the importance of standard fasting state or determination of maternal plasma glucose levels in patients undergoing Doppler flow evaluation of growth-retarded fetuses.
S Degani; R Levinsky; R Rabia; I Shapiro; M Sharf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  38     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1994  
Date Detail:
Created Date:  1994-12-12     Completed Date:  1994-12-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  41-4     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Bnai Zion Medical Center, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
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MeSH Terms
Birth Weight
Blood Flow Velocity
Blood Glucose / analysis*
Carotid Artery, Internal / embryology,  physiopathology,  ultrasonography
Cerebral Arteries / embryology,  physiopathology*,  ultrasonography
Embryonic and Fetal Development
Fetal Growth Retardation / physiopathology*,  ultrasonography
Fetus / blood supply
Gestational Age
Maternal Age
Ultrasonography, Doppler*
Ultrasonography, Prenatal*
Reg. No./Substance:
0/Blood Glucose

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