Document Detail

Maternal physiology and complications of multiple pregnancy.
MedLine Citation:
PMID:  16360493     Owner:  NLM     Status:  MEDLINE    
Approximately 1% to 3% of all pregnancies in the United States are multiple gestations. The vast majority (97-98%) are twin pregnancies. Multiple pregnancies constitute significant risk to both mother and fetuses. Antepartum complications-including preterm labor, preterm premature rupture of the membranes, intrauterine growth restriction, intrauterine fetal demise, gestational diabetes, and preeclampsia-develop in over 80% of multiple pregnancies as compared with approximately 25% of singleton gestations. This article reviews in detail the maternal physiologic adaptations required to support a multiple pregnancy and the maternal complications that develop when these systems fail or are overwhelmed.
Errol R Norwitz; Valentine Edusa; Joong Shin Park
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in perinatology     Volume:  29     ISSN:  0146-0005     ISO Abbreviation:  Semin. Perinatol.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-12-19     Completed Date:  2006-02-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801132     Medline TA:  Semin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  338-48     Citation Subset:  IM    
Department of Obstetrics, Gynecology & Reproductive Sciences, Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT 06520, USA.
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MeSH Terms
Fetal Death / physiopathology
Multiple Birth Offspring*
Obstetric Labor, Premature / physiopathology
Pregnancy Complications / physiopathology*
Pregnancy, Multiple / physiology*

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