Document Detail

Maternal oxygen administration for suspected impaired fetal growth.
MedLine Citation:
PMID:  12535388     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Fetal hypoxaemia is often a feature of fetal growth impairment. It has been suggested that perinatal outcome after suspected impaired fetal growth might be improved by giving mothers continuous oxygen until delivery.
OBJECTIVES: The objective was to assess the effects of maternal oxygen therapy in suspected impaired fetal growth on fetal growth and perinatal outcome.
SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register (November 2002).
SELECTION CRITERIA: Acceptably controlled trials comparing maternal oxygen therapy with no oxygen therapy in suspected impaired fetal growth.
DATA COLLECTION AND ANALYSIS: Eligibility and trial quality was assessed.
MAIN RESULTS: Three studies involving 94 women were included. Oxygenation compared with no oxygenation was associated with a lower perinatal mortality rate (relative risk: 0.50, 95% confidence interval 0.32 to 0.81). However, higher gestational age in the oxygenation groups may have accounted for the difference in mortality rates.
REVIEWER'S CONCLUSIONS: There is not enough evidence to evaluate the benefits and risks of maternal oxygen therapy for suspected impaired fetal growth. Further trials of maternal hyperoxygenation seem warranted.
L Say; A M Gülmezoglu; G J Hofmeyr
Related Documents :
2514198 - Individual growth curve standards in twins: growth in the second trimester.
22296248 - Critical issues in setting micronutrient recommendations for pregnant women: an insight.
14613578 - Genetic variants in apolipoprotein av alter triglyceride concentrations in pregnancy.
10776988 - The roles of placental growth hormone and placental lactogen in the regulation of human...
22216148 - Choriodecidual group b streptococcal inoculation induces fetal lung injury without intr...
6365448 - Immediate postplacental iud insertion: a randomized trial of sutured (lippes loop and t...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Cochrane database of systematic reviews     Volume:  -     ISSN:  1469-493X     ISO Abbreviation:  Cochrane Database Syst Rev     Publication Date:  2003  
Date Detail:
Created Date:  2003-01-21     Completed Date:  2003-03-27     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  100909747     Medline TA:  Cochrane Database Syst Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  CD000137     Citation Subset:  IM    
Department of Reproductive Health and Research, World Health Organization, 20 Avenue Appia, Geneva 27, Switzerland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Fetal Growth Retardation / prevention & control*
Infant Mortality
Infant, Newborn
Oxygen Inhalation Therapy*
Randomized Controlled Trials as Topic
Update Of:
Cochrane Database Syst Rev. 2000;(2):CD000137   [PMID:  10796154 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Vaccines for preventing malaria.
Next Document:  Prophylactic methylxanthines for extubation in preterm infants.